Формы, механизмы, энергия наномира. Сообщение 98 017

Online service PROTEIN PICOTECHNOLOGY

Заказ 2018-04-23 001:

http://www.uniprot.org/uniprot/Q9QZ04.fasta

>sp|Q9QZ04|MAGL2_MOUSE MAGE-like protein 2 OS=Mus musculus OX=10090 GN=Magel2 PE=1 SV=2
MSQLSTNLGDSSPPESPVPAVHSRPTVLMRAPPASSRAPPVPWDPPPVDLQAPMAAWQAP
QPAWEAPEGQLPAPVAQLAQPPGLGAPMVQAPPLGGGMAKPPTPGVLMVHQPPPGAPMAQ
SSTPGVLMLHPSVTGAPLAHPPPPGTPMTHPPGTSMAHPPPPPPPPPPPPPPGTPMTHPP
PPGTPMGHHPPPGNPMTHPPPGNPMVHPLTHGAPMVHGGPHGTPMPHVPITGTPIAQQPT
PGVLMAQQLTPGVLMVQPPAPGAPMVQPPPQAALMTQPAPSITPMAKPPGPGVVMIHPPG
ARGPIIQTPVSGAPMAQTVLPPGQPLATWAPQGQPLILQIQSQVIRAPPQVPSVPQAPQV
QLATPPGWQATTPNWQVTPQGWPATPLTWQATQVTWQAPTIAWQATQPGRQGHSTIRTGH
TPIRPGPAPLLRQIPPMIRQIQPVMRQAPPLIRQVPIRPAPHGIASQPQLWQVLPPPPPL
RQAPQARLLLPRVPGTGQVSTVPPVAQIHLVPQSGPQVPQTVLPAQLSIPIPVPQAAAQS
APRTVHCPPIIWQAPKGQAPVPQELPVPQELPVPQELPVPQEVPVPQEIPVPQEIPVPQE
LPVPQELPVPQELPVPQELPVPQELPVPQELPVPQELPVPQELPVPLEFQEVQQAQAVGW
RAPKVPPHFWQPVSAQEAQEQATQIAHVEQQQPFQGAPASSKALQTQLPTHQAQASGLQA
ELPSVQLQPSWQGPLPMLQAQPGASATLANFPRGSTRSRMAPSGEPGPSSLEPRGPPRER
RAPARDKKGPPKERMFIGATFCAPRGASASRAYVPTAWKNLPATSETFPATSRVFPSTSH
FQPASSNAFRGPSAASESPKSLPFALQDPYACVEALPAVPWVPYPDGNASSACKSVPAIL
MVAAAAPQASATAAEASKSSEPPRRPGKATRKKKHLEPKEDNCGHRLSSRDWRGPRTWGN
PSHSDWEIQRAMQLLGDRESLYTPQGLNDWGCPNTSRMPRSLEGPSTSRDQEFCGDSGGS
QTWMASEVPSVSRGSSAAQEDPDRESQPLSPLDERANALVQFLLVKDQAKVPVQLSEMVN
VVIREYKDDSLDIINRANTKLECTFGCQLKEVDTKTHTYIIVNKMAYPQCNLLASYLERP
KFSLLMVVLSLIFMKGYCIRENLLFSFLFQLGLDVQETSGLFRITKKLITSVFVRHRYLE
YRQIPFTEPAEYELLWGPRAFLETNRVHILRFLAALYENQPQIWSCQYLDSLAELEYKDA
NAAAEESHDSDDDAHDPTSSPHPH

Кушелев: Тут уже видна повторяющаяся последовательность, т.е. похоже на наличие программной спирали.

https://www.ebi.ac.uk/ena/data/view/AJ2 … play=fasta

>ENA|AJ243608|AJ243608.1 Mus musculus mRNA for ns7 protein, ortholog of the human nM15 gene.
AACTCAGCTGCCGACCCACCAGGCCCAAGCCTCTGGCTTGCAGGCAGAACTGCCTTCAGT
GCAGCTGCAGCCTTCTTGGCAAGGCCCACTGCCCATGTTGCAGGCCCAGCCTGGAGCCTC
TGCCACACTGGCAAACTTTCCCCGGGGCTCCACTCGATCACGTATGGCTCCATCAGGAGA
ACCTGGCCCCTCTTCTCTAGAACCTCGGGGCCCTCCTAGGGAACGTAGGGCACCTGCAAG
GGACAAAAAGGGTCCTCCAAAAGAGCGCATGTTCATTGGTGCCACTTTCTGTGCTCCAAG
GGGGGCATCAGCATCCAGGGCATACGTGCCAACTGCCTGGAAAAACTTGCCTGCCACATC
AGAGACCTTTCCTGCCACCTCAAGGGTCTTTCCATCTACCTCTCATTTCCAGCCTGCCTC
TTCTAATGCCTTTAGAGGTCCATCTGCCGCCTCAGAGAGCCCAAAGTCACTGCCATTTGC
TCTGCAGGATCCTTATGCCTGCGTAGAGGCCCTGCCTGCAGTTCCCTGGGTTCCGTATCC
AGATGGAAATGCCTCATCAGCATGTAAGTCAGTGCCTGCCATCTTGATGGTGGCAGCAGC
TGCCCCCCAGGCAAGTGCCACTGCTGCAGAGGCCTCTAAGTCTTCAGAGCCGCCAAGACG
CCCCGGCAAAGCCACCAGGAAGAAGAAGCATCTGGAACCCAAAGAAGACAACTGTGGCCA
CAGGCTCTCCTCACGTGACTGGCGGGGGCCCCGAACCTGGGGCAATCCCAGTCATTCTGA
CTGGGAGATTCAGAGGGCTATGCAGCTCCTGGGGGACCGGGAATCCCTCTACACTCCGCA
GGGCCTGAATGACTGGGGGTGCCCCAACACTTCTAGGATGCCAAGGAGCTTGGAGGGCCC
TAGCACTTCACGGGACCAGGAATTCTGTGGTGACTCGGGTGGGTCTCAGACATGGATGGC
TTCTGAGGTCCCAAGCGTCTCTCGGGGATCCAGTGCTGCTCAGGAGGACCCTGATAGGGA
GAGTCAGCCCTTATCTCCCTTAGATGAGAGAGCAAACGCTTTGGTGCAGTTTCTCTTGGT
CAAAGACCAAGCCAAGGTGCCTGTCCAGCTCTCGGAGATGGTAAATGTTGTCATCCGAGA
ATACAAAGACGACAGCTTAGACATCATCAACCGTGCCAACACTAAGCTGGAGTGCACCTT
TGGTTGTCAACTGAAGGAAGTTGACACCAAAACCCACACTTACATCATCGTCAACAAGAT
GGCGTACCCTCAGTGTAATTTGCTGGCATCCTATTTAGAGAGGCCAAAGTTCAGCCTCCT
GATGGTGGTCTTGAGCCTCATCTTTATGAAAGGCTACTGTATCAGGGAGAATCTGCTCTT
TAGTTTTCTGTTCCAGCTAGGGCTGGATGTCCAGGAGACAAGTGGTCTCTTCAGAATTAC
AAAGAAGCTCATCACCAGTGTGTTTGTGAGACACAGGTACCTAGAGTACAGGCAAATCCC
GTTCACTGAGCCTGCAGAATACGAGCTTCTCTGGGGGCCCCGGGCATTCCTCGAAACCAA
CAGGGTGCACATCTTGAGATTTTTGGCCGCACTCTACGAGAACCAGCCCCAGATCTGGTC
ATGCCAGTACCTTGACTCACTGGCAGAGTTAGAATACAAGGACGCAAATGCCGCCGCCGA
AGAGTCCCATGACAGCGATGATGATGCCCACGACCCCACCAGCAGTCCCCATCCTCACTA
ATAGACGTTACTAAGATGATTTTTATACTTGTGGGTCCAAAGCCAAAGGCAAAAGACAAT
GGGGGGTGGGGGACATTGTGCTTTCTGGTGTTTTTTGGTATTGTTCTCTGTGTATAAATT
TTACAGCCTGTTTTTATATTTGCCAAAGCTTTTGTACAGTTTTGTGAAATGTTGATTTAA
ACTGGCTGCTGTATTGTTTTGTATTTTGGTGTCTGTATTTTTTTAAATGAGATCTGTGAT
TCCCTGTTTGGTGTACTAATTGTAATGTTACAGTATCAGAGTTGTGCTGCCTTGTGTGTG
AAAAGAAATGACAGTTTATTTGTCTCGTTTTGTTTATGTAAAATCAGAATGTTTTTGGAT
GTTAATATGACTCATCGGTAAAATACTGTCTGGAGAAAAGTAAAGATCAATACTATATAA
ATATACTTTTAGCATAAAAA

Этот файл ошибочный. Он кодирует стоп-кодоны в структуре белка.

Вот исправленный, сделанный вручную:

>ENA|AJ243608|AJ243608.1 Mus musculus mRNA for ns7 protein, ortholog of the human nM15 gene.
atgttcattggtgccactttctgtgctccaaggggggcatcagcatccagggcatacgt
gccaactgcctggaaaaacttgcctgccacatcagagacctttcctgccacctcaagggt
ctttccatctacctctcatttccagcctgcctcttctaatgcctttagaggtccatctgc
cgcctcagagagcccaaagtcactgccatttgctctgcaggatccttatgcctgcgtaga
ggccctgcctgcagttccctgggttccgtatccagatggaaatgcctcatcagcatgtaa
gtcagtgcctgccatcttgatggtggcagcagctgccccccaggcaagtgccactgctgc
agaggcctctaagtcttcagagccgccaagacgccccggcaaagccaccaggaagaagaa
gcatctggaacccaaagaagacaactgtggccacaggctctcctcacgtgactggcgggg
gccccgaacctggggcaatcccagtcattctgactgggagattcagagggctatgcagct
cctgggggaccgggaatccctctacactccgcagggcctgaatgactgggggtgccccaa
cacttctaggatgccaaggagcttggagggccctagcacttcacgggaccaggaattctg
tggtgactcgggtgggtctcagacatggatggcttctgaggtcccaagcgtctctcgggg
atccagtgctgctcaggaggaccctgatagggagagtcagcccttatctcccttagatga
gagagcaaacgctttggtgcagtttctcttggtcaaagaccaagccaaggtgcctgtcca
gctctcggagatggtaaatgttgtcatccgagaatacaaagacgacagcttagacatcat
caaccgtgccaacactaagctggagtgcacctttggttgtcaactgaaggaagttgacac
caaaacccacacttacatcatcgtcaacaagatggcgtaccctcagtgtaatttgctggc
atcctatttagagaggccaaagttcagcctcctgatggtggtcttgagcctcatctttat
gaaaggctactgtatcagggagaatctgctctttagttttctgttccagctagggctgga
tgtccaggagacaagtggtctcttcagaattacaaagaagctcatcaccagtgtgtttgt
gagacacaggtacctagagtacaggcaaatcccgttcactgagcctgcagaatacgagct
tctctgggggccccgggcattcctcgaaaccaacagggtgcacatcttgagatttttggc
cgcactctacgagaaccagccccagatctggtcatgccagtaccttgactcactggcaga
gttagaatacaaggacgcaaatgccgccgccgaagagtcccatgacagcgatgatgatgc
ccacgaccccaccagcagtccccatcctcactaat

В этом белке попался семидольный ритм, но структура не периодическая...